ABSTRACT
@#Cavernous lymphangioma is a congenital malformation of lymphatic system causing dilated lymphatic sinuses that involve the skin and subcutaneous tissues. This was an interesting case of dystrophic macrodactyly of the left ring and little finger in a 18-month-old girl who presented with swollen and sausage like fingers deformity which turned out to be an isolated cavernous lymphangioma. This tumor, although rare to occur in the extremeties, must be differentiated from other congenital vascular lesions of the hand that include arteriovenous malformations and hemangiomas. Diagnosis should be solely based on histopathological analysis of the excised tissue mass. Surgical excision is usually necessary for satisfactory functional and cosmetic outcome.
ABSTRACT
Background: Tuberculosis is one of the most common opportunistic infections among people with HIV infection. Detection of pulmonary tuberculosis by sputum-based techniques includes microscopy and culture. However, in people living with HIV, sputum production is scanty and also the sputum contains less number of bacilli due to fewer cavitations, thereby decreasing the sensitivity and specificity of sputum microscopy as a diagnostic tool. Aim of the study: In this study, we assess the usefulness of CBNAAT in the early detection of pulmonary tuberculosis and its incidence by using CBNAAT in smear-negative HIV patients using mycobacterial culture in Lowenstein Jensen medium as Gold Standard. Materials and methods: The study was conducted in the Department of Cardiothoracic Surgery, Government Mohan Kumaramangalam Medical College Hospital. Data were collected from 150 HIV infected patients who tested sputum smear negative. Sputum samples were then sent for CBNAAT and sputum culture for mycobacteria. Results: Of the 150 patients enrolled, 28(18.66%) of them were detected with MTB by CBNAAT; whereas sputum culture could detect 38(25.33%) of them. Thus, compared to sputum smear, CBNAAT increases TB detection by 18.66% and sputum culture increases by 25.33%. The sensitivity of CBNAAT in our study was 73.68% and the incidence of smear-negative pulmonary TB in the study population by using CBNAAT was 18.66%. Conclusion: CBNAAT is a highly sensitive and diagnostic stool for the diagnosis of pulmonary TB and it is of immense help in the early diagnosis of smear-negative pulmonary TB in HIV infected patients. Therefore, CBNAAT should be used as the initial test in HIV infected patients suspected with pulmonary TB.
ABSTRACT
Background: In the treatment of multiple warts, there is no single treatment that is 100% effective and different modalities of treatment need to be combined. Aim: To evaluate the efficacy of homologous autoimplantation therapy in the treatment of multiple warts. Methods: A total of 60 patients of multiple verruca vulgaris and palmo-plantar warts were enrolled. Homologous autoimplantation was done after harvesting full-depth wart tissue. Patients were followed upto a period of 6 months. Resolution of warts within a period of 3 months after procedure was considered successful. Results: All the 60 patients were available for follow-up. A total of 28 patients of verruca vulgaris (70%) and 16 patients of palmo-plantar warts (80%) showed resolution of warts within 3 months, accounting for a total clearance rate of 73.3%. Majority of the responders (91%) showed resolution of warts within 2 months. Conclusion: This study demonstrates that homologous autoimplantation could be an effective, simple modality of treatment for multiple warts.
ABSTRACT
Vitiligo is known to be associated with a variety of dermatoses and systemic diseases. We describe a case of vitiligo developing in a patient having cutaneous amyloidosis. To our knowledge this is the first report of its kind in the literature.